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potassium tetraborate tetrahydrate is a naturally occurring mineral salt that has been used for centuries. It is found in many parts of the world and is an important chemical component in various industrial applications. It is also a widely used dietary supplement.
Synthesis
The synthesis of potassium tetraborate tetrahydrate can be accomplished in several ways. One method involves mixing potassium tetraborate tetrahydrate and a small amount of potassium hydroxide (KOH). The reaction is performed at 700 degC and the product is water and potassium tetraborate tetrahydrate. Another method involves dissolving POTASSIUM TETRABORATE in a solution of KOH.
Antibacterial activity
The ability of PTB to inhibit bacterial growth is largely dependent on its interaction with lipid components in the bacterial cell membrane. Bacterial cells treated with PTB were unable to grow as rapidly and showed a reduction in cell density and adherence to the surface of the nutrient broth culture medium. This reduction in bacterial growth was accompanied by an increase in permeability of the bacterial membrane to propidium iodide. This increase in permeability was confirmed by flow cytometry using Syto9 and PI staining.
Bacterial soft rot caused by Dickeya and Pectobacterium is a devastating disease of vegetables and ornamental plants that results in high losses. Several strategies have been developed to help control this disease.
Inhibition of bacterial colony development
PTB was found to inhibit the growth of a variety of strains of Dickeya and Pectobacterium spp. The concentrations of PTB required to inhibit bacterial growth were found to range from 10 to 100 mM. Conclusion: These findings suggest that PTB can be a useful alternative to conventional management strategies for preventing bacterial soft rot.