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CaCO3 Nanoparticles and Their Applications

Posted on 2023-06-01

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caco3 nanoparticles

Calcium Carbonate (CaCO3) is a white soluble solid with a melting point of 825 degC, thermal conductivity of 5.526 W/(mK) at 273K and pH of 8. It is one of the most important biominerals in the human body and plays a critical role in the formation of bone. It is also an important component of cement and mortar compounds.

Nanoparticles with high surface area can be used for a variety of applications including imaging, drug delivery and alloying. Nanoparticles have been reported to be excellent candidates for polarization-dependent image contrast mapping and X-ray scattering, and can enable new applications in the fields of biosurgery, chemotherapeutics and anticarcinogenic drugs.

Moreover, these crystalline nanoparticles can be used as nucleating agents in isotactic polypropylene (iPP) to enhance its crystallization behavior and improve its thermal properties. Interestingly, caco3 nanoparticles with different shapes (spherical and elongated) show a remarkable influence on the thermal properties of iPP and crystallization rate.

Functionalized Erythrocytes by In Situ Synthesis of Intracellular Stealth Mineral Nanoscaffolds

The synthesis of CaCO3 nanoscaffolds inside erythrocytes is achieved through a two-step sequential permeation of Ca2+ and CO32- ions. The resulting well-dispersed intracellular nanodots (NDs) are 3.90 nm in size, which is significantly smaller than those produced through traditional methods. These NDs have a unique structure and are highly refractory to cytotoxic ions in the blood stream, such as lead. They can remove 80% of lead ions in a blood poisoning model in vitro and reduce the Pb2+ accumulation in kidney and liver of mice in vivo. This study may provide a new strategy for constructing “cyborg cells” that integrate the biological function of erythrocytes with the functionality of nanomaterials.

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